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The Center for Integrated Molecular Brain Imaging (Cimbi) is a research center funded by the Lundbeck Foundation. The research in the Center focuses on the neural bases of personality dimensions that predispose individuals to affective and substance use disorders, with special emphasis on the serotonergic neurotransmitter system. The serotonergic neurotransmitter system is involved in a large variety of psychophysiological functions, including feeding, mood, aggression, and pain. Serotonin is also a critical neurotransmitter in brain development and in the generation and regulation of emotional behaviour. Finally, it plays a prominent role in the inhibition of impulses. In Cimbi both PET and MRI are employed in studies of human subjects, and these are complemented with relevant studies using animal models. Advanced informatics techniques, new tracer compounds, and novel serotonergic challenge paradigms are also being developed within the center. The work venues span several institutions in Copenhagen as well as several collaborating laboratories in Europe and the U.S. |
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The Center for Integrated Molecular Brain Imaging is founded on a collaboration between a number of research institutions in Copenhagen. These institutions form the core of Cimbi and all the research activities in Cimbi involve one or more of these institutions. The core institutions are distributed among the Copenhagen University Hospitals, the Technical University of Denmark and the University of Copenhagen. Furthermore, a number of other Danish and international institutions are associated with Cimbi as collaborators in one or more subprojects in Cimbi. The institutions involved in Cimbi research therefore span many scientific fields and provide the strong foundation needed to carry out the diverse activities undertaken in Cimbi.
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The Cimbi steering group consists of the center director, the PI's of the different Cimbi projects and the center manager. In the first life cycle of Cimbi (Cimbi-I, 2006-10), the steering group had a management meeting once a month. In the second lifecycle of Cimbi (Cimbi-II, 2011-15), the Council of Investigators (COI) group meetings have replaced the monthly steering group meetings and the steering group now has a more withdrawn role, primarily taking care of broader issues like economy and new strategic initiatives. The steering group now has only one scheduled meeting a year, right after the annual meeting.
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The Council of Investigators (COI) group consists of the senior researchers and postdocs with the daily responsibility for the different projects within Cimbi. The COI group meets once a month to mutually inform about status in all projects and also discuss practical and scientific aspects.
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